LIME1 Antibody

Size

100ug

Clone Number

Aliases

LIME1 antibody; LIME antibody; LP8067 antibody; Lck-interacting transmembrane adapter 1 antibody; Lck-interacting membrane protein antibody; Lck-interacting molecule antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9H400

Immunogen

Recombinant Human Lck-interacting transmembrane adapter 1 protein (170-295AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200

Background

Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T-cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

LIME1

Research Areas

Immunology