LGI1 Antibody

Size

100ul

Clone Number

Aliases

ADLTE antibody; ADPAEF antibody; ADPEAF antibody; Epitempin 1 antibody; EPITEMPIN antibody; Epitempin-1 antibody; EPT antibody; ETL1 antibody; IB1099 antibody; leucine rich glioma inactivated 1 antibody; Leucine rich glioma-inactivated protein 1 antibody; Leucine-rich glioma-inactivated protein 1 antibody; LGI1 antibody; LGI1_HUMAN antibody; OTTHUMP00000020121 antibody; OTTHUMP00000020122 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O95970

Immunogen

Recombinant Human Leucine-rich glioma-inactivated protein 1 protein (35-285AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

LGI1

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience; Cancer