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ABCbiolab

SKU:ABCCS01152

LGALS3 Monoclonal Antibody

LGALS3 Monoclonal Antibody

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Size

100ug

Clone Number

3F2E2

Aliases

Lectin, galactoside-binding, soluble, 3; LGALS3; CBP35; GAL3; GALBP; GALIG; LGALS2; MAC2; Galectin 3

Immunogen Species

Human

UniProt ID

P17931

Immunogen

Recombinant Human Galectin 3(GAL-3)

Raised in

Mouse

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:500

Background

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis By similarity. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

Clonality

Monoclonal

Isotype

IgG2b

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

LGALS3

Research Areas

Neuroscience; Cell biology

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