ABCbiolab
SKU:ABCCS01152
LGALS3 Monoclonal Antibody
LGALS3 Monoclonal Antibody
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Size
100ug
Clone Number
3F2E2
Aliases
Lectin, galactoside-binding, soluble, 3; LGALS3; CBP35; GAL3; GALBP; GALIG; LGALS2; MAC2; Galectin 3
Immunogen Species
Human
UniProt ID
P17931
Immunogen
Recombinant Human Galectin 3(GAL-3)
Raised in
Mouse
Species Reactivity
Human, Mouse
Tested Applications
ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:500
Background
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis By similarity. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
Clonality
Monoclonal
Isotype
IgG2b
Purification Method
>95%, Protein G purified
Conjugate
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Stroage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names
LGALS3
Research Areas
Neuroscience; Cell biology
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