LETM1 Antibody

Size

100ug

Clone Number

Aliases

LETM 1 antibody; LETM1 and EF hand domain containing protein 1; mitochondrial antibody; LETM1 and EF-hand domain-containing protein 1 antibody; Letm1 antibody; LETM1_HUMAN antibody; Leucine zipper EF hand containing transmembrane protein 1 antibody; Leucine zipper-EF-hand-containing transmembrane protein 1 antibody; Mdm38 homolog antibody; mitochondrial antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O95202

Immunogen

Recombinant Human Mitochondrial proton/calcium exchanger protein (443-543AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200

Background

Mitochondrial proton/calcium antiporter that mediates proton-dependent calcium efflux from mitochondrion (PubMed:19797662). Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain (PubMed:18628306). Required for the maintenance of the tubular shape and cristae organization (PubMed:18628306). In contrast to SLC8B1/NCLX, does not constitute the major factor for mitochondrial calcium extrusion (PubMed:24898248).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

LETM1

Research Areas

Tags & Cell Markers; Metabolism