LDOC1 Polyclonal Antibody

Ab type

Primary antibody

Background

The leucine zipper down-regulated in cancer 1 encoded by LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human LDOC1. AA range:21-70

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

16968

synonyms

LDOC1; BCUR1; Protein LDOC1; Leucine zipper protein down-regulated in cancer cells