LAT Antibody

Size

100ul

Clone Number

Aliases

36 kDa phospho tyrosine adapter protein antibody; 36 kDa phospho-tyrosine adapter protein antibody; 36 kDa phospho-tyrosine adaptor protein antibody; LAT 1 antibody; lat antibody; LAT_HUMAN antibody; LAT1 antibody; Linker for activation of T cells antibody; Linker for activation of T cells family member 1 antibody; linker for activation of T cells; transmembrane adaptor antibody; Linker for activation of T-cells family member 1 antibody; p36 38 antibody; p36-38 antibody; pp36 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O43561

Immunogen

Recombinant Human Linker for activation of T-cells family member 1 protein (28-233AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

LAT

Research Areas

Immunology; Signal transduction