Kv4.2(Phospho Ser616) Polyclonal Antibody

Ab type

Primary antibody

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as i

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human Kv4.2 (phospho Ser616)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

70577

synonyms

Potassium voltage-gated channel subfamily D member 2; KCND2; KIAA1044; Potassium voltage-gated channel subfamily D member 2; Voltage-gated potassium channel subunit Kv4.2