Kv1.1 potassium channel Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthetic Peptide of Kv1.1 potassium channel

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Potassium voltage-gated channel subfamily A member 1 ;Voltage-gated K;+ channel HuKI;Voltage-gated potassium channel HBK1;Voltage-gated potassium channel subunit Kv1.1; KCNA1; Potassium voltage-gated channel subfamily A member 1; Voltage-gated K;+ channel HuKI; Voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv1.1