Ksr2 Polyclonal Antibody

Ab type

Primary antibody

Background

Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human KSR2. AA range:671-720

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

107632

synonyms

KSR2; Kinase suppressor of Ras 2; hKSR2