KLK8 Antibody

Size

100ug

Clone Number

Aliases

Brain serine protease 1 antibody; BSP1 antibody; hK8 antibody; HNP antibody; HPN antibody; Kallikrein 8 (neuropsin/ovasin) antibody; Kallikrein related peptidase 8 antibody; Kallikrein-8 antibody; Kallikrein8 antibody; KLK 8 antibody; Klk8 antibody; KLK8 protein type 1 antibody; KLK8 protein type 2 antibody; KLK8_HUMAN antibody; Neuropsin antibody; neuropsin type 1 antibody; Neuropsin type 1; included antibody; Neuropsin type 2 antibody; Neuropsin type 2; included antibody; Neuropsin; mouse; homolog of antibody; NP antibody; NRPN antibody; Ovasin antibody; PRO322 antibody; Protease serine 19 antibody; PRSS 19 antibody; PRSS19 antibody; Serine protease 19 antibody; Serine protease kallikrein antibody; Serine protease kallikrein/ovasin/neuropsin antibody; Serine protease TADG 14 antibody; Serine protease TADG-14 antibody; Serine protease TADG14 antibody; TADG 14 antibody; TADG14 antibody; Tumor associated differentially expressed gene 14 antibody; Tumor associated differentially expressed gene 14 protein antibody; Tumor-associated differentially expressed gene 14 protein antibody; UNQ283 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O60259

Immunogen

Recombinant Human Kallikrein-8 protein (87-241AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

KLK8

Research Areas

Cancer; Cell biology; Signal transduction