KLF4 Antibody

Size

100ul

Clone Number

Aliases

Endothelial Kruppel like zinc finger protein antibody; Epithelial zinc finger protein EZF antibody; EZF antibody; GKLF antibody; gut Kruppel-like factor antibody; Gut-enriched krueppel-like factor antibody; KLF antibody; KLF4 antibody; KLF4_HUMAN antibody; Krueppel-like factor 4 antibody; Kruppel like factor 4 (Epithelial zinc finger protein EZF) (Gut enriched Krueppel like factor) antibody; Kruppel like factor 4 (gut) antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O43474

Immunogen

Recombinant Human Krueppel-like factor 4 protein (30-230AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Background

Transcription factor; can act both as activator and as repressor. Binds the 5\\\'-CACCC-3\\\' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

KLF4

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Cardiovascular; Developmental biology; Stem cells