KLF15 Antibody

Size

100ul

Clone Number

Aliases

Kidney enriched Kruppel like factor antibody; Kidney-enriched krueppel-like factor antibody; KKLF antibody; KKLF protein antibody; KLF 15 antibody; KLF15 antibody; KLF15_HUMAN antibody; Krueppel-like factor 15 antibody; Kruppel like factor 15 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UIH9

Immunogen

Recombinant Human Krueppel-like factor 15 protein (1-260AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Transcriptional regulator that binds to the GA element of the CLCNKA promoter. Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart (By similarity). Is a repressor of CTGF expression, involved in the control of cardiac fibrosis. It is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A and GATA4 (By similarity). Involved in podocyte differentiation (By similarity). Inhibits MYOCD activity. Is a negative regulator of TP53 acetylation. Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

KLF15

Research Areas

Epigenetics and Nuclear Signaling; Cardiovascular