KLF12 Polyclonal Antibody

Ab type

Primary antibody

Background

Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. Krueppel-like factor 12 encoded by KLF12 is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human KLF12.

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

44240

synonyms

KLF12; AP2REP; HSPC122; Krueppel-like factor 12; Transcriptional repressor AP-2rep