KIF20B Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

Cancer/testis antigen 90 antibody; CT90 antibody; KI20B_HUMAN antibody; KIF20B antibody; Kinesin-like protein KIF20B antibody; Kinesin-related motor interacting with PIN1 antibody; KRMP1 antibody; M-phase phosphoprotein 1 antibody; MPHOSPH1 antibody; MPP 1 antibody; Mpp1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q96Q89

Immunogen

Recombinant Human Kinesin-like protein KIF20B protein (1607-1731AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth (By similarity). Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

KIF20B

Research Areas

Cell biology; Signal transduction