KIF13A Antibody

Size

100ug

Clone Number

Aliases

bA500C11.2 antibody; FLJ27232 antibody; Homolog of mouse KIF13A mannose 6 phosphate receptor transporter antibody; KI13A_HUMAN antibody; KIF 13A antibody; Kif13a antibody; Kinesin family member 13A antibody; Kinesin like protein KIF13A antibody; Kinesin like protein RBKIN antibody; Kinesin-like protein KIF13A antibody; Kinesin-like protein RBKIN antibody; RBKIN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9H1H9

Immunogen

Recombinant Human Kinesin-like protein KIF13A protein (1383-1537AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Background

Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

KIF13A

Research Areas

Signal transduction