KDM6B Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

Histone demethylase JMJD3 antibody; JmjC domain containing protein 3 antibody; JmjC domain-containing protein 3 antibody; Jumonji D3 antibody; Jumonji domain containing 3 antibody; Jumonji domain containing 3 histone lysine demethylase antibody; Jumonji domain containing protein 3 antibody; Jumonji domain-containing protein 3 antibody; Kdm6b antibody; KDM6B_HUMAN antibody; KIAA0346 antibody; Lysine demethylase 6B antibody; Lysine K specific demethylase 6B antibody; Lysine specific demethylase 6B antibody; Lysine-specific demethylase 6B antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O15054

Immunogen

Recombinant Human Lysine-specific demethylase 6B protein (1530-1682AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Histone demethylase that specifically demethylates \'Lys-27\' of histone H3, thereby playing a central role in histone code (PubMed:17825402, PubMed:17851529, PubMed:17713478, PubMed:18003914). Demethylates trimethylated and dimethylated H3 \'Lys-27\' (PubMed:17825402, PubMed:17851529, PubMed:17713478, PubMed:18003914). Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529). Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation (PubMed:17825402).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

KDM6B

Research Areas

Epigenetics and Nuclear Signaling