KDM5C Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

DXS1272E antibody; Histone demethylase JARID1C antibody; JARID1C antibody; JmjC domain containing protein SMCX antibody; Jumonji AT rich interactive domain 1C antibody; Jumonji, AT rich interactive domain 1C (RBP2 like) antibody; Jumonji/ARID domain-containing protein 1C antibody; KDM5C antibody; KDM5C_HUMAN antibody; Lysine (K) specific demethylase 5C antibody; Lysine-specific demethylase 5C antibody; MRX13 antibody; MRXJ antibody; MRXSCJ antibody; MRXSJ antibody; Protein SmcX antibody; Protein Xe169 antibody; rbp2 like protein antibody; Selected cDNA on X antibody; SMCX antibody; Smcx homolog X chromosome antibody; SmcX protein antibody; Smcy homolog X linked antibody; XE169 antibody; Xe169 protein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P41229

Immunogen

Recombinant Human Lysine-specific demethylase 5C protein (45-324AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Histone demethylase that specifically demethylates \'Lys-4\' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 \'Lys-9\', H3 \'Lys-27\', H3 \'Lys-36\', H3 \'Lys-79\' or H4 \'Lys-20\'. Demethylates trimethylated and dimethylated but not monomethylated H3 \'Lys-4\'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

KDM5C

Research Areas

Epigenetics and Nuclear Signaling