KCNMB3 Antibody

Size

100ul

Clone Number

Aliases

BK channel subunit beta 3 antibody; BK channel subunit beta-3 antibody; BKbeta 3 antibody; BKbeta3 antibody; Calcium activated potassium channel beta 3 subunit antibody; Calcium activated potassium channel subfamily M subunit beta 3 antibody; Calcium activated potassium channel subunit beta 3 antibody; Calcium-activated potassium channel antibody; Calcium-activated potassium channel subunit beta-3 antibody; Charybdotoxin receptor subunit beta 3 antibody; Charybdotoxin receptor subunit beta-3 antibody; EG435726 antibody; Gm5707 antibody; Hbeta 3 antibody; Hbeta3 antibody; K(VCA)beta 3 antibody; K(VCA)beta-3 antibody; KCMB3_HUMAN antibody; KCNMB 2 antibody; KCNMB 3 antibody; KCNMB2 antibody; KCNMB3 antibody; KCNMBL antibody; Large conductance voltage and Ca2+ activated potassium channel Maxi K beta 3 subunit antibody; Maxi K channel subunit beta 3 antibody; Maxi K channel subunit beta-3 antibody; Potassium channel, calcium-activated large conductance, subfamily M, beta member 3 antibody; Potassium large conductance calcium activated channel beta 3 subunit antibody; Potassium large conductance calcium activated channel subfamily M beta member 3 antibody; Slo beta 3 antibody; Slo-beta-3 antibody; subfamily M subunit beta-3 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NPA1

Immunogen

Recombinant Human Calcium-activated potassium channel subunit beta-3 protein (82-207AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:50-1:200

Background

Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Alters the functional properties of the current expressed by the KCNMA1 channel. Isoform 2, isoform 3 and isoform 4 partially inactivate the current of KCNBMA. Isoform 4 induces a fast and incomplete inactivation of KCNMA1 channel that is detectable only at large depolarizations. In contrast, isoform 1 does not induce detectable inactivation of KCNMA1. Two or more subunits of KCNMB3 are required to block the KCNMA1 tetramer.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Antigen Affinity purified & Affinity purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

KCNMB3

Research Areas

Signal Transduction