KCNE1 Antibody

Size

100ug

Clone Number

Aliases

Delayed rectifier potassium channel subunit IsK antibody; Human cardiac delayed rectifier potassium channel protein antibody; IKs producing slow voltage gated potassium channel subunit beta Mink antibody; IKs producing slow voltage-gated potassium channel subunit beta Mink antibody; ISK antibody; JLNS 2 antibody; JLNS antibody; JLNS2 antibody; KCNE 1 antibody; KCNE1 antibody; KCNE1_HUMAN antibody; LQT 5 antibody; LQT5 antibody; MGC33114 antibody; Minimal potassium channel antibody; MinK antibody; Potassium voltage gated channel Isk related family member 1 antibody; Potassium voltage gated channel Isk related subfamily member 1 antibody; Potassium voltage gated channel subfamily E member 1 antibody; Potassium voltage-gated channel subfamily E member 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P15382

Immunogen

Recombinant Human Potassium voltage-gated channel subfamily E member 1 protein (85-129AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:19219384). Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

KCNE1

Research Areas

Neuroscience; Cardiovascular