KAT2A Antibody

Size

100ul

Clone Number

Aliases

1110051E14Rik antibody; AW212720 antibody; EC 2.3.1.48 antibody; GCN 5 antibody; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2 antibody; Gcn5 antibody; GCN5 general control of amino-acid synthesis 5-like 2 (yeast) antibody; GCN5L2 antibody; general control of amino acid synthesis 5-like 2 antibody; General control of amino acid synthesis protein 5-like 2 antibody; General control of amino acid synthesis, yeast, homolog-like 2 antibody; HGCN5 antibody; Histone acetyltransferase GCN5 antibody; Histone acetyltransferase KAT2A antibody; hsGCN5 antibody; K(lysine) acetyltransferase 2A antibody; KAT2 A antibody; KAT2A antibody; KAT2A_HUMAN antibody; Lysine acetyltransferase 2A antibody; MGC102791 antibody; PCAF-b antibody; STAF97 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q92830

Immunogen

Recombinant Human Histone acetyltransferase KAT2A protein (302-537AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Background

Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. Also acetylates non-histone proteins, such as CEBPB (PubMed:17301242). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat\'s transactivating activity and may help inducing chromatin remodeling of proviral genes.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

KAT2A

Research Areas

Epigenetics and Nuclear Signaling