Jagged1 Polyclonal Antibody

Ab type

Primary antibody

Background

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human JAG1. AA range:981-1030

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

133799

synonyms

Protein jagged-1; JAG1; JAGL1; Protein jagged-1; Jagged1; hJ1; CD339