ITSN2 Antibody

Size

100ug

Clone Number

Aliases

ITSN2 antibody; KIAA1256 antibody; SH3D1B antibody; SWAP antibody; Intersectin-2 antibody; SH3 domain-containing protein 1B antibody; SH3P18 antibody; SH3P18-like WASP-associated protein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NZM3

Immunogen

Recombinant Human Intersectin-2 protein (940-1209AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200

Background

Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). Plays a role in dendrite formation by melanocytes (PubMed:23999003).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ITSN2

Research Areas

Signal transduction