ITM2B Antibody

Size

100ug

Clone Number

Aliases

ABRI antibody; ABri/ADan amyloid peptide antibody; BRI 2 antibody; BRI antibody; BRI2 antibody; BRICD 2B antibody; BRICD2B antibody; BRICHOS domain containing 2B antibody; E25B antibody; E3 16 antibody; E3-16 antibody; FBD antibody; imBRI2 antibody; Immature BRI2 antibody; Integral membrane protein 2B antibody; ITM 2B antibody; ITM2B antibody; ITM2B_HUMAN antibody; Protein E25B antibody; RDGCA antibody; Transmembrane protein BRI antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y287

Immunogen

Recombinant Human Integral membrane protein 2B protein (81-148AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

Plays a regulatory role in the processing of the beta-amyloid A4 precursor protein (APP) and acts as an inhibitor of the beta-amyloid peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ITM2B

Research Areas

Neuroscience