ITGAV Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1| beta 3| beta 5| beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human ITGAV (light chain| Cleaved-Asp891)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

115280

synonyms

ITGAV ;light chain; Cleaved-Asp891; Integrin alpha-V; Vitronectin receptor subunit alpha; CD antigen CD51; Integrin alpha-V heavy chain; Integrin alpha-V light chain;