ITGA5  Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection| the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.|Belongs to the integrin alpha chain family.|Contains 7 FG-GAP repeats.|subunit:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with HIV-1 Tat. Interacts with RAB21.|

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human ITGA5 (heavy chain| Cleaved-Arg894)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

115390

synonyms

ITGA5 ;heavy chain; Cleaved-Arg894; Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD antigen CD49e; Integrin alpha-5 heavy chain; Integrin alpha-5 light chain;