ITGA3 Antibody

Size

100ug

Clone Number

Aliases

AA407068 antibody; Antigen identified by monoclonal antibody J143 antibody; CD49 antigen like family member C antibody; CD49 antigen-like family member C antibody; CD49c antibody; CD49c antigen antibody; FLJ34631 antibody; FLJ34704 antibody; FRP 2 antibody; FRP-2 antibody; FRP2 antibody; Galactoprotein B3 antibody; GAP B3 antibody; GAPB3 antibody; Integrin alpha 3 antibody; Integrin alpha-3 light chain antibody; Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody; ITA3_HUMAN antibody; ITGA 3 antibody; Itga3 antibody; MSK18 antibody; VCA 2 antibody; VCA2 antibody; Very late activation protein 3 receptor alpha 3 subunit antibody; VL3A antibody; VLA 3 alpha chain antibody; VLA 3 subunit alpha antibody; VLA-3 subunit alpha antibody; VLA3a antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P26006

Immunogen

Recombinant Human Integrin alpha-3 protein (168-276AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ITGA3

Research Areas

Signal transduction