IRX3 Antibody

Size

100ug

Clone Number

Aliases

AI894186 antibody; Homeodomain protein IRXB1 antibody; Iroquois class homeodomain protein IRX 1 antibody; Iroquois homeobox 3 antibody; Iroquois homeobox protein 3 antibody; Iroquois-class homeodomain protein irx-3 antibody; IRX 1 antibody; irx3 antibody; IRX3_HUMAN antibody; IRXB1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P78415

Immunogen

Recombinant Human Iroquois-class homeodomain protein IRX-3 protein (285-378AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IRX3

Research Areas

Neuroscience