ABCbiolab
SKU:ABCB13038
IRK6 Polyclonal Antibody
IRK6 Polyclonal Antibody
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Ab type
Primary antibody
Background
This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability.
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
Synthesized peptide derived from part region of human protein
Storage Stability
-20°C for 1 year
Concentration
1 mg/ml
MolecularWeight_Da
synonyms
G protein-activated inward rectifier potassium channel 2 ;GIRK-2;BIR1;Inward rectifier K;+ channel Kir3.2;KATP-2;Potassium channel, inwardly rectifying subfamily J member 6
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