IRF-3 Polyclonal Antibody

Ab type

Primary antibody

Background

IRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human IRF3. AA range:362-411

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

47219

synonyms

IRF3; Interferon regulatory factor 3; IRF-3