IRF-3 Polyclonal Antibody

Ab type

Primary antibody

Background

IRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human IRF3. AA range:351-400

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

47219

synonyms

IRF3; Interferon regulatory factor 3; IRF-3