IQCB1 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

IQ calmodulin-binding motif containing 1 antibody; IQ calmodulin-binding motif-containing protein 1 antibody; IQ motif containing B1 antibody; Iqcb1 antibody; IQCB1_HUMAN antibody; KIAA0036 antibody; Nephrocystin-5 antibody; NPHP5 antibody; p53 and DNA damage-regulated IQ motif protein antibody; SLSN5 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q15051

Immunogen

Recombinant Human IQ calmodulin-binding motif-containing protein 1 protein (445-598AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Involved in ciliogenesis. The function in an early step in cilia formation depends on its association with CEP290/NPHP6 (PubMed:21565611, PubMed:23446637). Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2 and BBS5 in the complex, and in ciliary targeting of selected BBSome cargos. May play a role in controlling entry of the BBSome complex to cilia possibly implicating CEP290/NPHP6 (PubMed:25552655).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IQCB1

Research Areas

Neuroscience; Signal transduction