ABCbiolab
SKU:ABCB02999
IP3KA Polyclonal Antibody
IP3KA Polyclonal Antibody
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Ab type
Primary antibody
Background
Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.
Reactivity
Human;Mouse;Rat
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
The antiserum was produced against synthesized peptide derived from human IP3KA. AA range:396-445
Storage Stability
-20°C for one year
Concentration
1 mg/ml
MolecularWeight_Da
51009
synonyms
ITPKA; Inositol-trisphosphate 3-kinase A; Inositol 1; 4,5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase A
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