INTS6 Antibody

Size

100ug

Clone Number

Aliases

DBI 1 antibody; DBI-1 antibody; DBI1 antibody; DDX26 antibody; DDX26A antibody; DEAD box protein antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 26 antibody; Deleted in cancer 1 antibody; DICE1 antibody; DKFZp434B105 antibody; HDB antibody; Int6 antibody; INT6_HUMAN antibody; Integrator complex subunit 6 antibody; INTS 6 antibody; ints6 antibody; Notchl2 antibody; OTTHUMP00000018439 antibody; OTTHUMP00000215034 antibody; OTTHUMP00000215036 antibody; Protein DDX26 antibody; Protein deleted in cancer 1 antibody; RNA helicase HDB antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UL03

Immunogen

Recombinant Human Integrator complex subunit 6 protein (571-795AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:20-1:200

Background

Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3\\\'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth (PubMed:15254679, PubMed:16239144).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

INTS6

Research Areas

Epigenetics and Nuclear Signaling; Cancer