INTS3 Antibody

Size

100ug

Clone Number

Aliases

INTS3 antibody; C1orf193 antibody; C1orf60 antibody; Integrator complex subunit 3 antibody; Int3 antibody; SOSS complex subunit A antibody; Sensor of single-strand DNA complex subunit A antibody; SOSS-A antibody; Sensor of ssDNA subunit A antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q68E01

Immunogen

Recombinant Human Integrator complex subunit 3 protein (901-1043AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:50-1:200

Background

Component of the Integrator (INT) complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3\\\'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

INTS3

Research Areas

Epigenetics and Nuclear Signaling