Ini1 Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by SMARCB1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1) is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. SMARCB1 has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for SMARCB1.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthetic peptide from human protein at AA range: 331-380

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

44141

synonyms

SMARCB1 BAF47 INI1 SNF5L1