IMP cyclohydrolase Monoclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.

Reactivity

Human,Rb

Clonality

Monoclonal

Host

Mouse

Isotype

IgG

Immunogen

Purified recombinant human IMP cyclohydrolase protein fragments expressed in E.coli.

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

N/A

synonyms

ATIC; PURH; OK/SW-cl.86; Bifunctional purine biosynthesis protein PURH