IL36RN Antibody

Size

100ul

Clone Number

Aliases

AI413231 antibody; Family of interleukin 1 delta antibody; FIL1 antibody; FIL1 delta antibody; FIL1(DELTA) antibody; FIL1D antibody; Fil1delta antibody; I36RA_HUMAN antibody; IL 1 delta antibody; IL 1 related protein 3 antibody; IL 1F5 (IL 1HY1, FIL1 delta, IL 1RP3, IL 1L1, IL 1 delta) antibody; Il 1h3 antibody; IL 1HY1 antibody; IL 1L1 antibody; IL 1ra homolog antibody; IL 1ra homolog, IL1F5 (Canonical product IL 1F5a) antibody; IL 1RP3 antibody; IL-1 delta antibody; IL-1-related protein 3 antibody; IL-1F5 antibody; IL-1HY1 antibody; IL-1L1 antibody; IL-1ra homolog 1 antibody; IL-1RP3 antibody; IL1F5 antibody; IL1HY1 antibody; IL1L1 antibody; IL1RP3 antibody; IL36RA antibody; IL36RN antibody; Interleukin 1 delta antibody; Interleukin 1 family member 5 (delta) antibody; Interleukin 1 family member 5 antibody; Interleukin 1 HY1 antibody; Interleukin 1 like protein 1 antibody; Interleukin 1 receptor antagonist homolog 1 antibody; Interleukin 36 receptor antagonist antibody; Interleukin-1 delta antibody; Interleukin-1 family member 5 antibody; Interleukin-1 HY1 antibody; Interleukin-1 receptor antagonist homolog 1 antibody; Interleukin-1-like protein 1 antibody; Interleukin-36 receptor antagonist protein antibody; MGC29840 antibody; PSORP antibody; RP23-176J12.6 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UBH0

Immunogen

Recombinant Human Interleukin-36 receptor antagonist protein (1-155AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IL36RN

Research Areas

Immunology