IL34 Antibody

Size

100ug

Clone Number

Aliases

C16orf77 antibody; Chromosome 16 open reading frame 77 antibody; FPT025 antibody; IL 34 antibody; IL-34 antibody; Il34 antibody; IL34_HUMAN antibody; Interleukin 34 antibody; Interleukin-34 antibody; Interleukin34 antibody; MGC34647 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q6ZMJ4

Immunogen

Recombinant Human Interleukin-34 protein (191-240AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Background

Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IL34

Research Areas

Immunology