IL33 Antibody

Size

100ug

Clone Number

Aliases

C9orf26 antibody; CHROMOSOME 9 OPEN READING FRAME 26 antibody; DKFZp586H0523 antibody; DVS27 antibody; DVS27 related protein antibody; IL 1F11 antibody; IL 33 antibody; IL-1F11 antibody; IL-33 antibody; IL1F11 antibody; IL33 antibody; IL33_HUMAN antibody; Interleukin 1 family member 11 antibody; Interleukin 33 antibody; INTERLEUKIN 33 NFHEV antibody; Interleukin 33 precursor antibody; Interleukin-1 family member 11 antibody; Interleukin-33 (109-270) antibody; Interleukin33 antibody; NF HEV antibody; NF-HEV antibody; NFEHEV antibody; NFHEV antibody; Nuclear factor for high endothelial venules antibody; Nuclear factor from high endothelial venules antibody; OTTHUMP00000021041 antibody; RP11 575C20.2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O95760

Immunogen

Recombinant Human Interleukin-33 protein (123-276AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an \\\"alarmin\\\", that amplifies immune responses during tissue injury (PubMed:17853410, PubMed:18836528).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IL33

Research Areas

Cardiovascular; Immunology