IL31RA Antibody

Size

100ul

Clone Number

Aliases

Class I cytokine receptor antibody; CRL 3 antibody; CRL antibody; CRL3 antibody; Cytokine receptor like 3 antibody; Cytokine receptor-like 3 antibody; GLM R antibody; GLM-R antibody; GLMR antibody; Gp130 like monocyte receptor antibody; GP130 like receptor antibody; Gp130-like monocyte receptor antibody; Gp130-like receptor antibody; GPL antibody; HGLM R antibody; HGLM-R antibody; HGLMR antibody; IL 31 receptor subunit alpha antibody; IL 31R subunit alpha antibody; IL 31RA antibody; IL-31 receptor subunit alpha antibody; IL-31R subunit alpha antibody; IL-31R-alpha antibody; IL-31RA antibody; IL31 receptor subunit alpha antibody; IL31R subunit alpha antibody; IL31R_HUMAN antibody; IL31RA antibody; Interleukin 31 receptor A antibody; interleukin 31 receptor subunit alpha antibody; Interleukin-31 receptor subunit alpha antibody; MGC125346 antibody; PLCA 2 antibody; PLCA2 antibody; PRO21384 antibody; Soluble type I cytokine receptor CRL3 antibody; ZcytoR17 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8NI17

Immunogen

Recombinant Human Interleukin-31 receptor subunit alpha protein (1-300AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 (PubMed:11877449, PubMed:14504285, PubMed:15627637, PubMed:15194700). May function in skin immunity (PubMed:15184896). Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (By similarity). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IL31RA

Research Areas

Epigenetics and Nuclear Signaling; Immunology; Signal transduction