IL23R Antibody

Size

100ug

Clone Number

Aliases

IL 23R antibody; IL-23 receptor antibody; IL-23R antibody; IL23 Receptor antibody; Il23r antibody; IL23R_HUMAN antibody; Interleukin 23 receptor antibody; Interleukin-23 receptor antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q5VWK5

Immunogen

Recombinant Human Interleukin-23 receptor protein (15-125AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IL23R

Research Areas

Epigenetics and Nuclear Signaling; Immunology; Signal transduction