IL23A Antibody

Size

100ug

Clone Number

Aliases

IL 23 A antibody; IL 23 antibody; IL 23 subunit alpha antibody; IL 23A antibody; IL 23p19 antibody; IL-23 subunit alpha antibody; IL-23-A antibody; IL-23p19 antibody; IL12B antibody; IL23 antibody; Il23a antibody; IL23A_HUMAN antibody; IL23P19 antibody; interleukin 12B antibody; Interleukin 23 alpha subunit p19 antibody; Interleukin 23 p19 subunit antibody; interleukin 23 subunit alpha antibody; interleukin 23 subunit p19 antibody; interleukin six; G CSF related factor antibody; Interleukin-23 subunit alpha antibody; Interleukin-23 subunit p19 antibody; JKA3 induced upon T cell activation antibody; MGC79388 antibody; P19 antibody; SGRF antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NPF7

Immunogen

Recombinant Human Interleukin-23 subunit alpha protein (20-155AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IL23A

Research Areas

Cancer; Immunology