IL22RA1 Antibody

Size

100ul

Clone Number

Aliases

CRF2 9 antibody; CRF2-9 antibody; Cytokine receptor class-II member 9 antibody; cytokine receptor classII member 9 antibody; Cytokine receptor family 2 member 9 antibody; I22R1_HUMAN antibody; IL-22 receptor subunit alpha-1 antibody; IL-22R-alpha-1 antibody; IL-22RA1 antibody; IL22 Receptor Alpha antibody; IL22R antibody; IL22R1 antibody; Il22ra1 antibody; ILTIF R1 chain antibody; Interleukin 22 Receptor alpha 1 antibody; Interleukin 22 Receptor antibody; Interleukin-22 receptor subunit alpha-1 antibody; ZcytoR11 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8N6P7

Immunogen

Recombinant Human Interleukin-22 receptor subunit alpha-1 protein (16-230AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Background

Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IL22RA1

Research Areas

Immunology; Signal transduction