IL21 Antibody

Size

100ul

Clone Number

Aliases

CVID11 antibody; IL 21 antibody; IL-21 antibody; Il21 antibody; IL21_HUMAN antibody; Interleukin 21 antibody; Interleukin-21 antibody; interleukin-21 isoform antibody; Interleukin21 antibody; OTTHUMP00000164088 antibody; Za11 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9HBE4

Immunogen

Recombinant Human Interleukin-21 protein (25-162AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG1 and IgG3 in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IL21

Research Areas

Cancer; Immunology