IL1RL2 Antibody

Size

100ug

Clone Number

Aliases

IL 1 receptor related protein 2 antibody; IL 1Rrp2 antibody; IL 36R antibody; IL-1Rrp2 antibody; IL-36 receptor antibody; IL1 receptor related protein 2 antibody; IL1R rp2 antibody; IL1R-rp2 antibody; Il1rl2 antibody; IL1RRP2 antibody; IL36R antibody; ILRL2_HUMAN antibody; Interleukin 1 receptor like 2 antibody; Interleukin 1 receptor related protein 2 antibody; Interleukin-1 receptor-like 2 antibody; Interleukin-1 receptor-related protein 2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9HB29

Immunogen

Recombinant Human Interleukin-1 receptor-like 2 protein (20-218AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IL1RL2

Research Areas

Immunology