IL1R2 Antibody

Size

100ul

Clone Number

Aliases

IL1 Receptor II antibody; Antigen CDw121b antibody; CD121 antibody; CD121 antigen-like family member B antibody; CD121b antibody; CD121B Antigen antibody; CDw121b antibody; IL 1 type II receptor antibody; IL-1R-2 antibody; IL-1R-beta antibody; IL-1R2 antibody; IL-1RT-2 antibody; IL-1RT2 antibody; IL1R Beta antibody; Il1r-2 antibody; IL1R2 antibody; IL1R2_HUMAN antibody; IL1R2c antibody; IL1RB antibody; Interleukin 1 receptor type II variant 3 antibody; Interleukin 1 receptor; beta; type II antibody; Interleukin 1 receptor; type II antibody; Interleukin-1 receptor beta antibody; Interleukin-1 receptor type 2 antibody; Interleukin-1 receptor type II antibody; MGC137383 antibody; MGC47725 antibody; OTTHUMP00000207969 antibody; p68 antibody; Type II interleukin-1 receptor; beta antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P27930

Immunogen

Recombinant Human Interleukin-1 receptor type 2 protein (20-320AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB; Recommended dilution: WB:1:200-1:1000

Background

Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IL1R2

Research Areas

Cardiovascular; Immunology; Stem cells