IL1R1 Antibody

Size

100ug

Clone Number

Aliases

Antigen CD121a antibody; CD121 antigen-like family member A antibody; CD121a antibody; CD121a antigen antibody; D2S1473 antibody; IL 1 antibody; IL 1R 1 antibody; IL 1R alpha antibody; IL 1RT1 antibody; IL-1R-1 antibody; IL-1R-alpha antibody; IL-1RT-1 antibody; IL-1RT1 antibody; IL1 inhibitor antibody; IL1 Receptor I antibody; IL1R antibody; IL1R1 antibody; IL1R1_HUMAN antibody; IL1RA antibody; IL1RN antibody; IL1RT1 antibody; Interleukin 1 receptor alpha type 1 antibody; Interleukin 1 receptor antagonist protein (IRAP) antibody; Interleukin 1 receptor type I antibody; Interleukin receptor 1 antibody; Interleukin-1 receptor alpha antibody; Interleukin-1 receptor type 1 antibody; Interleukin-1 receptor type I antibody; p80 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P14778

Immunogen

Recombinant Human Interleukin-1 receptor type 1 protein (18-320AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200

Background

Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IL1R1

Research Areas

Cardiovascular; Immunology; Stem cells