IL1AP Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection| tissue damage| or stress| by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms| one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human IL1AP

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

IL1AP; Interleukin-1 receptor accessory protein; IL-1 receptor accessory protein; IL-1RAcP; Interleukin-1 receptor 3; IL-1R-3; IL-1R3