IL17RA Antibody

Size

100ug

Clone Number

Aliases

CANDF5 antibody; CD217 antibody; CD217 antigen antibody; CDw217 antibody; CTLA8 antibody; HIL 17R antibody; hIL17R antibody; I17RA_HUMAN antibody; IL 17 receptor A antibody; IL 17 receptor antibody; IL 17RA antibody; IL-17 receptor A antibody; IL-17RA antibody; IL17 antibody; IL17A receptor antibody; IL17R antibody; IL17RA antibody; IMD51 antibody; Interleukin 17 receptor A antibody; Interleukin-17 receptor A antibody; MGC10262 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q96F46

Immunogen

Recombinant Human Interleukin-17 receptor A protein (552-743AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200

Background

Receptor for IL17A (PubMed:17911633, PubMed:9367539). Receptor for IL17F (PubMed:19838198, PubMed:17911633). Binds to IL17A with higher affinity than to IL17F (PubMed:17911633). Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC (PubMed:16785495). Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC (PubMed:18684971). Receptor for IL17C as part of a heterodimeric complex with IL17RE (PubMed:21993848). Activation of IL17RA leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6 (PubMed:16785495, PubMed:17911633, PubMed:18684971).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IL17RA

Research Areas

Immunology