IL12RB1 Antibody

Size

100ug

Clone Number

Aliases

CD212 antibody; cluster of differentiation 212 antibody; I12R1_HUMAN antibody; IL-12 receptor beta component antibody; IL-12 receptor subunit beta-1 antibody; IL-12R subunit beta-1 antibody; IL-12R-beta-1 antibody; IL-12RB1 antibody; IL12 receptor beta component antibody; IL12RB antibody; Il12rb1 antibody; IMD3 antibody; IMD30 antibody; Interleukin 12 receptor beta 1 chain antibody; Interleukin 12 receptor subunit beta 1 antibody; Interleukin-12 receptor subunit beta-1 antibody; MGC34454 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P42701

Immunogen

Recombinant Human Interleukin-12 receptor subunit beta-1 protein (119-280AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IL12RB1

Research Areas

Immunology